I take xanax (alprazolam) and valium will grapefruit juice have a side effect?

Minor: Grapefruit juice inhibits the liver enzymes that break down certain medicines, resulting in a small increase in the medicine's effect. This definitely occurs with valium; there is some uncertainly whether it affects xanax (alprazolam) as much, or at all. It takes a lot of grapefruit juice (at least a pint, probably more) to have this effect. Tell your doc if you drink lots of grapefruit juice regularly.

Benzodiazapine: WHY do you take 2 different benzodiazapines? If you use Xanax with either grapefruit or grapefruit juice, the level of alprazolam in blood can increase & cause an increase in side effects like dizziness, sedation & confusion. This is considered a moderate clinically significant issue per Drugs.Com Taking valium with grapefruit juice also has potential for moderate clinical issue.