A member asked:

How is progeria genetically transferred from parent to offspring?

4 doctors weighed in across 2 answers

Most new mutations: Progeria is a self limited process with most recorded cases appearing as new mutations in families that have other normal children. There are rare sibships reported indicating an autosomal recessive form exists.Most don't survive their teens.The oldest on record died at 27.

Answered 12/9/2013

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Progeria: The majority of cases are due to new genetic mutations. However, there are some inherited cases (rarer) due to mosaicism in a parent. This can occur when a parent who does not have progeria has a small percentage of cells that have that the genetic mutation.

Answered 9/7/2020

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