A member asked:

Does autosomal recessive polycystic kidney disease of one parent could be genetically transmissible to one of the children and what is the percentage?

4 doctors weighed in across 2 answers

Can transmit: For a recessive disorder you need an abnormal gene from each parent. The parent without arpckd may have one abnormal gene but has one normal one. This is called being a "carrier". The parent with arpckd has 2 abnormal genes. If the parent without the disease is a carrier, there is a 50% chance that the child will have arpckd. If the parent is not a carrier, there is a 0% chance.

Answered 2/19/2014

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ARPKD: Autosomal recessive kidney disease will transmit to a child from a parent who has ARPKD only if both parents carry the trait. Percentage is low.

Answered 8/7/2014

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