Warts on my toes were treated with liquid nitrogen, after two years they came back, i think it's spreading now to my hand, what else can i use?

Many things...: You can use the liquid nitrogen again, liquid nitrous oxide (this is what i like to use), topical acids, dermal scraping. You can also try oral cimetadine (400 mg three times a day for 12-16 weeks). This is very safe and had the side effect of getting rid of warts for many people of adult size and weight (japma november 1, 1995 vol. 85 no. 11 717-718 ).

CO2 Laser: Pulsed co2 laser is used for ablation of warts. The warts are lasered down to the level of fat and your skin heals itself. Also some anti cancer medications, bleomycin can used. Both of the treatments are expensive. I also have used hydrochloric acid to burn recurring warts. This procedure is slightly more painful than freezing them but I have gotten very good results.

No One Way.: The reason there are so many ways to treat warts is because all the methods are not 100 % effective. All methods are limited by availability, cost, debilitation considerations, experience and the list goes on and on. After treating thousands of warts in just about any imaginable, I recommend that the earlier you start treatment by any method, the better the results.