A 48-year-old member asked:
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what is the difference between the medications neurontin (gabapentin) and lyrica (pregabalin)?

1 doctor answer
Dr. STEPHEN GIROUX
39 years experience Pharmacology
Basically price: Gabapentin is older and available generically, so much cheaper. Lyrica (pregabalin) is newer dosages are different and somewhat less frequent than gabapentin. Lyrica (pregabalin)- because it is newer has more indications ( labelled uses- ie postherpetic neuralgia and fibromyalgia) but Gabapentin will work just as well. Gabapentin(neurontin) was originally marketed for seizure disorders but more commonly used for neuralgi.
Answered on Oct 4, 2018
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Related questions:

A 42-year-old member asked:
Dr. Peter Forster
35 years experience Psychiatry
Cost and absorption: Gabapentin (neurontin) and Pregabalin (lyrica) are structurally similar and have similar effects pharmacologically. Pregabalin is absorbed better and ... Read More
3
3 thanks
A 35-year-old male asked:
Dr. Paul Grin
Dr. Paul Grin answered
35 years experience Pain Management
Only cost and dosage: Lyrica (pregabalin) is effective as gabapentin for neuropathic pain migraine headache, however costs more.
A 48-year-old member asked:
Dr. Catherine Willner
34 years experience Neurology
Depends on problem: These are anticonvulsants (seizure medications). They are also used for pain. So, the answer depends on why these are used. Sometimes other anticon ... Read More
4
4 thanks
A 24-year-old female asked:
Dr. Colin Sanner
19 years experience Neurology
Mechanisms of action: Meds that act on calcium channels = Gabapentin and lyrica; likely no new meds with that same mechanism of action for a while. But, existing meds for n ... Read More
1
1 thank

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