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A member asked:
Define nuclear pleomorphism and how it indicates malignancy in tumors.?
6 doctors weighed in across 2 answers
Many sizes: Variability in the size and shapes of cells. When there is increased nuclear pleomorphism, this typically indicates an increase in aggressiveness. Hope this helps.
Answered 3/26/2013
5.6k views
A complex issue: Nuclear morphology, variation in size, shape, staining characteristics, relation to cell size, are some of the features evaluated by pathologists in making a diagnosis of malignancy. The criteria vary by tissue and tumor type and require years of training and practice to master, not something that can be explained in 400 characters.
Answered 9/16/2012
5.6k views
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