What is the complication of high esr?

None: High ESR does not cause any problems. If there is an underlying disease it may cause problems and the severity of problems may be related to the height of the esr.

ESR is a marker of: Erythrocyte sedimentation rate (ESR) is a marker of inflammation, thus high inflammatory processes cause ESR to be higher. Infections, cancers, uncontrolled rheumatologic diseases, and endovascular inflammation(i.e. Arteritis) are examples. Thus, elevated ESR values suggest inflammatory conditions which should be sought and treated. Esr is not a complication, but a marker! consult doc. Good luck.