A member asked:

Diffuse increase in intraepithelial lymphocytes. how likely is it celiac disease? what other tests should be done?

3 doctors weighed in across 2 answers
Dr. John Chiu answered

Too vague a question: I trust you are referring to some biopsy findings and thus need to know where the biopsy was obtained. The definitive diagnosis for celiac disease is a small intestinal biopsy. Certain blood tests such as IgA ttg is said to be over 90% sensitive in detecting gluten sensitivity provided that you are not avoiding gluten when the blood sample is obtained.

Answered 11/12/2019

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Blood test: IgA antibody to tissue transglutaminase and/or IgG antibody to deamidated gliadin could be diagnostic.

Answered 11/14/2019

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