What are the signs and symptoms of approaching kidney failure?

A lot of signs: Usually nausea, vomiting , weight loss , shortness of breath , trembling of hands, palor and mood disorders, problem sleeping are mostly the signs and symptoms of impending renal failure.

Fluid retention: As the kidneys fail it is common (but not universal) to have difficulty with fluid balance. Many people begin to swell due to the kidneys inability to get rid of adequate fluid, even with the use of diuretics (like furosemid). This leads to ankle/leg swelling (edema), weight gain, difficulty breathing and elevated blood pressure. All of these will likely improve with dialysis or transplantation.