Is it safe to take ibuprofen while pregnant?

No: Ibuprofen is an NSAID and you should not take this in pregnancy unless directed by your obstetrician for a few very specific indications. For fever, headaches and pains that you might take Ibuprofen for outside of pregnancy take tylenol (acetaminophen) for in pregnancy unless you are allergic to tylenol (acetaminophen) or have liver disease. Alleve is also not to be taken in pregnancy.

Not really: Anything in small moderation is not necessarily harmful while pregnant, even occassional caffeine, alcohol, or Ibuprofen (nsaids). But that doesn't mean these things are safe during pregnancy, as they can all have side effects if taken excessively or persistently. If taken repeatedly while pregnant, nsaids can cause early closure of the ductus arteriosus, which is necessary for fetal circulation.