A member asked:

Does anyone know how long methotrexate stays in your system?

A doctor has provided 1 answer
Dr. Thomas Namey answered

Specializes in Rheumatology

10 weeks!: Methotrexate, itself, is virtually gone in several days. But more active metabolites, called Methotrexate polyglutamates, stay inside body tissue for 2&1/2 months. If you are on mtx for arthitis, or other rheumatology problem, you should wate that long before trying to conceive.

Answered 5/28/2020

5.6k views

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