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A member asked:

Does anyone know how long methotrexate stays in your system?

A doctor has provided 1 answer
Dr. Thomas Namey answered

Specializes in Rheumatology

10 weeks!: Methotrexate, itself, is virtually gone in several days. But more active metabolites, called Methotrexate polyglutamates, stay inside body tissue for 2&1/2 months. If you are on mtx for arthitis, or other rheumatology problem, you should wate that long before trying to conceive.

Answered 5/28/2020

5.6k views

Thank

Related Questions

A member asked:

Are all ectopic pregnancies surgery treated with methotrexate?. How long does this drug take to flush out the system before trying again. Thanks

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A member asked:

Hi, I'm on Plasmaquine and Methotrexate 7.5mg x 1 per week for arthritis. I'm concerned that the Methotrexate may weaken my immune system and make me more vulnerable to Covid-19. Would it not be safer to discontinue use untill the threat has passed?

3 doctors weighed in across 2 answers

A member asked:

When one is using methotrexate for arthritis or lupus, is the goal to supress the immune system so the auto diff labs are below normal or stay wnl?

A doctor has provided 1 answer

A member asked:

Take methotrexate for connective tissue disease.Is goal to suppress my immune system so auto diff labs are below normal or stay wnl but below my norm?

7 doctors weighed in across 2 answers

A member asked:

I had methotrexate for an ectopic pregnancy 6 weeks ago. 2 weeks ago my HCG was down to 96 and I had my period. The HCG level is now at 11 and I am getting positive ovulation tests. Can you actually ovulate with HCG still in your system?

A doctor has provided 1 answer

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