Leptin: Is a hormone that regulates energy intake & expenditure, including appetite & metabolism. It acts on the hypothalamus part of the brain where it inhibits appetite by counbteracting the effects of neuropeptide y & anandamide (both are feeding stimulants, and also by increasing synthesis of the appetite suppressant alpha-msh. Lack of leptin causes uncontrollable food intake & obesity.
Answered 2/22/2013
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