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A 36-year-old member asked:

what is an immunoglobulin?

2 doctor answers3 doctors weighed in
Dr. Andrew Murphy
Allergy and Immunology 29 years experience
Part of immune sys: Immunoglobulins are proteins that we make that are part of our immune system. There are four main types igg, igm, IgA and ige all of which perform different functions.
Dr. Gurmukh Singh
Pathology 49 years experience
Early response: Antibody type. There five types of immunoglobulins and IgM is first one produced in response to an infection. The others being igg, iga, IgD and ige.

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A 34-year-old member asked:

Do foods contain immunoglobulins?

2 doctor answers3 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
Probably not...: Immunoglobulins (antibodies) are proteins used by the immune system to identify and eliminate unknown cells (like germs). They are found in body fluids like blood, tears, saliva, & breast milk. If foods are consumed raw or barely cooked, there is a chance that you are also consuming immunoglobulins from that animal. In most cases, the cooking or pasteurization process destroys these proteins.
A 38-year-old member asked:

What does a high immunoglobulin mean ?

1 doctor answer2 doctors weighed in
Dr. Steven Machtinger
Allergy and Immunology 44 years experience
How high?: Minimally elevated probably not worth worrying about. Very or moderately high requires a test - serum immunoelectrophoresis - to rule-out multiple myeloma. Minimally high bears repeating twice a year.
A 42-year-old member asked:

What are structural differences of the immunoglobulins?

1 doctor answer3 doctors weighed in
Dr. Michael P Vaughn
Allergy and Immunology 34 years experience
Antibodies: Structural difference exist for all classes of antibody; igg, igm, iga, ige and igd. The structure of the antibody is insignificant when compared to the common ability to bind specifically to an antigen, typically a foreign protein or carbohydrate. Structural differences do account for different immune cell binding properties and also complement fixation (which helps in defense).
A 45-year-old member asked:

What is immunoglobulin diversity generated by?

1 doctor answer2 doctors weighed in
Dr. Amit Golding
Rheumatology 19 years experience
Combinatorial: The genes that encode our antigen receptors (immunoglobulin and T cell receptors) are made up of hundreds of gene segments. These "V-D-J" segments recombine in potentially millions of combinations so that each immune cell has one final version that makes a unique receptor. This process is random but if the cell encounters its antigen it will be activated and can turn into a "memory" cell.
A 50-year-old member asked:

What is an immunoglobulin fold?

1 doctor answer1 doctor weighed in
Dr. Al Hegab
Dr. Al Hegabanswered
Allergy and Immunology 40 years experience
Immunoglobulin fold: is part of the complex molecular structure of the Ig antibody

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Last updated May 11, 2018

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