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A 42-year-old member asked:

what are structural differences of the immunoglobulins?

1 doctor answer3 doctors weighed in
Dr. Michael P Vaughn
Allergy and Immunology 34 years experience
Antibodies: Structural difference exist for all classes of antibody; igg, igm, iga, ige and igd. The structure of the antibody is insignificant when compared to the common ability to bind specifically to an antigen, typically a foreign protein or carbohydrate. Structural differences do account for different immune cell binding properties and also complement fixation (which helps in defense).

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A 33-year-old member asked:

Is there any side effects of immunoglobulin intravenous medication?

2 doctor answers4 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 35 years experience
Possiby: Intravenous immunoglobulin (ivig) is a blood product collected from donations from hundreds of individuals, so there is the theoretical possibility of typical transfusion problems i.e. Infection, reaction etc. In the U.S. However production of this product is so controlled and processing involves, detergent washing and treating the product, so it is less likely to cause problems.
CA
A 24-year-old member asked:

Who are the people that need to take Rh immunoglobulin?

2 doctor answers4 doctors weighed in
Dr. Michael P Vaughn
Allergy and Immunology 34 years experience
Rh sensitization: Rh sensitization can only occur if an rh negative person is exposed to rh positive blood. This can happen with blood transfusions or from rh positive fetal blood spill-over into the mother's blood stream during delivery. Once formed, these antibodies can harm future pregnancies. If the baby's dad is rh positive, rh negative mom's should get an injection of rh antibody to stop her production.
CA
A 34-year-old member asked:

Do foods contain immunoglobulins?

2 doctor answers3 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
Probably not...: Immunoglobulins (antibodies) are proteins used by the immune system to identify and eliminate unknown cells (like germs). They are found in body fluids like blood, tears, saliva, & breast milk. If foods are consumed raw or barely cooked, there is a chance that you are also consuming immunoglobulins from that animal. In most cases, the cooking or pasteurization process destroys these proteins.
A 38-year-old member asked:

What does a high immunoglobulin mean ?

1 doctor answer2 doctors weighed in
Dr. Steven Machtinger
Allergy and Immunology 44 years experience
How high?: Minimally elevated probably not worth worrying about. Very or moderately high requires a test - serum immunoelectrophoresis - to rule-out multiple myeloma. Minimally high bears repeating twice a year.
A 36-year-old member asked:

What does a high immunoglobulin level mean for you?

1 doctor answer1 doctor weighed in
Dr. David Rosenthal
Allergy and Immunology 21 years experience
It depends: There are several types of immunoglobulin, igg, iga, IgM and ige. Having a "high" level of each of them could mean different things. It is also important to know if it is a "high" overall level, or a "high" level of a specific kind of igg, iga, igm, or ige. In general, a high ige means "allergy". High igg/a/m can mean different things depending on their specificity (total or specific).

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Last updated Sep 13, 2012

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