A 45-year-old member asked:
what is immunoglobulin diversity generated by?
1 doctor answer • 2 doctors weighed in
Dr. Amit Goldinganswered
Rheumatology 19 years experience
Combinatorial: The genes that encode our antigen receptors (immunoglobulin and T cell receptors) are made up of hundreds of gene segments. These "V-D-J" segments recombine in potentially millions of combinations so that each immune cell has one final version that makes a unique receptor. This process is random but if the cell encounters its antigen it will be activated and can turn into a "memory" cell.
3.5k viewsReviewed >2 years ago
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Similar questions
CA
A 33-year-old member asked:
Is there any side effects of immunoglobulin intravenous medication?
2 doctor answers • 4 doctors weighed in
Dr. Stephen Kimuraanswered
Allergy and Immunology 35 years experience
Possiby: Intravenous immunoglobulin (ivig) is a blood product collected from donations from hundreds of individuals, so there is the theoretical possibility of typical transfusion problems i.e. Infection, reaction etc. In the U.S. However production of this product is so controlled and processing involves, detergent washing and treating the product, so it is less likely to cause problems.
6.4k viewsReviewed >2 years ago
CA
A 24-year-old member asked:
Who are the people that need to take Rh immunoglobulin?
2 doctor answers • 4 doctors weighed in
Dr. Michael P Vaughnanswered
Allergy and Immunology 34 years experience
Rh sensitization: Rh sensitization can only occur if an rh negative person is exposed to rh positive blood. This can happen with blood transfusions or from rh positive fetal blood spill-over into the mother's blood stream during delivery. Once formed, these antibodies can harm future pregnancies. If the baby's dad is rh positive, rh negative mom's should get an injection of rh antibody to stop her production.
6.4k viewsReviewed >2 years ago
CA
A 34-year-old member asked:
Do foods contain immunoglobulins?
2 doctor answers • 3 doctors weighed in
Dr. Alex Martinezanswered
Specializes in Allergy
Probably not...: Immunoglobulins (antibodies) are proteins used by the immune system to identify and eliminate unknown cells (like germs). They are found in body fluids like blood, tears, saliva, & breast milk. If foods are consumed raw or barely cooked, there is a chance that you are also consuming immunoglobulins from that animal. In most cases, the cooking or pasteurization process destroys these proteins.
6.3k viewsReviewed >2 years ago
Chelmsford, MA
A 40-year-old female asked:
Recently found out, that I have an immune disease. They want to do rplacement via subq gammaglobulin...Anyone tell me how it works & side effects?
2 doctor answers • 5 doctors weighed in
Dr. Ed Friedlanderanswered
Pathology 44 years experience
CVI?: This is most likely common variable immunodeficiency or one of its close relatives. It's quite common. Get two physicians' opinions. If they agree, you owe it to yourself to accept this gift. Cvi patients have difficulty making one class or another of antibodies, but thankfully other people's will work fine for you.
6.1k viewsReviewed >2 years ago
A 38-year-old member asked:
What does a high immunoglobulin mean ?
1 doctor answer • 2 doctors weighed in
Dr. Steven Machtingeranswered
Allergy and Immunology 44 years experience
How high?: Minimally elevated probably not worth worrying about. Very or moderately high requires a test - serum immunoelectrophoresis - to rule-out multiple myeloma. Minimally high bears repeating twice a year.
5.8k viewsReviewed >2 years ago
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Last updated Nov 27, 2014
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