A 45-year-old member asked:
What is immunoglobulin diversity generated by?
1 doctor answer • 2 doctors weighed in
Combinatorial: The genes that encode our antigen receptors (immunoglobulin and T cell receptors) are made up of hundreds of gene segments. These "V-D-J" segments recombine in potentially millions of combinations so that each immune cell has one final version that makes a unique receptor. This process is random but if the cell encounters its antigen it will be activated and can turn into a "memory" cell.
3.5k viewsReviewed >2 years ago
Last updated Nov 27, 2014
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.