How safe is progesterone tablets for pcos fertility treatment?

Safe; sometimes used: Progesterone or artificial versions (progestins) can be safely used to induce a period for women with pcos who have very few periods (less than 4 a year) or no periods. It does not improve your chances of conceiving because it induces bleeding, not ovulation (egg release). Progesterone can also be given for low Progesterone levels in the 2nd half of a cycle, or to support an early pregnancy.

OTC or Rx?: Over the counter (no prescription) can be harmful or dangerous because it's unregulated by the fda. Prescription Progesterone has some risks which should be discussed with the prescribing doctor before taking. It's generally a risk vs benefit scenario. Progesterone alone does not boost fertility in pcos patients.