A member asked:

What is the method of action of aspirin and ibuprofen?

A doctor has provided 1 answer
Dr. David Rosenfeld answered

Specializes in Pain Management

See below: Aspirin is a nonsteroidal anti-inflammatory drug (nsaids), but differs from most other nsaids in the mechanism of action. Though it, and others in its group called the salicylates, have similar effects (antipyretic, anti-inflammatory, analgesic) to the other nsaids and inhibit the same enzyme cyclooxygenase, Aspirin (but not the other salicylates) does so in an irreversible manner.

Answered 3/26/2017

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