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What is the method of action of aspirin and ibuprofen?

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Dr. David Rosenfeld
Pain Management 27 years experience
See below: Aspirin is a nonsteroidal anti-inflammatory drug (nsaids), but differs from most other nsaids in the mechanism of action. Though it, and others in its group called the salicylates, have similar effects (antipyretic, anti-inflammatory, analgesic) to the other nsaids and inhibit the same enzyme cyclooxygenase, Aspirin (but not the other salicylates) does so in an irreversible manner.

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Last updated Mar 26, 2017

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