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A 53-year-old member asked:

what's the difference between arimidex and femara (letrozole)?

3 doctor answers5 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
Very little: Both of these drugs are aromatase inhibitors and are used to treat post-menopausal hormone-sensitive breast cancer patients. Their chemical structure is remarkably similar. No study has ever compared these two drugs "head-to-head", so it is hard to recommend one over the other. If one of my patient's side effects are so severe that they are contemplating stopping the med, i switch to another.
Dr. Barry Rosen
General Surgery 34 years experience
3 choices: There is a 3rd aromatase inhibitor (ai) on the market called aromasin (exemestane). The structure of this ai is slightly different and it binds irreversably to aromatase, however no clinical difference is evident with this ai in comparison to the others. Furthermore, all 3 are currently available as generics.
Dr. Devon Webster
Medical Oncology 22 years experience
Different companies: These drugs have different structures but act in the same way. Both are aromatase inhibitors. Arimidex (anastrozole) (generic name anastrazole) and Femara (generic name letrozole) may have different side effects in different women, as well as different costs. They can be used interchangeably.

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A 26-year-old member asked:

What are the similarities and differences between tamoxifen and femara (letrozole)?

2 doctor answers4 doctors weighed in
Dr. Devon Webster
Medical Oncology 22 years experience
Different action: Tamoxifen blocks the estrogen receptor, while Femara (letrozole) blocks the formation of estrogen. Estrogen levels are not lowered by tamoxifen, but they are lowered by femara (letrozole). Both cause hot flashes, bone loss, depression, memory problems and decreased libido. Tamoxifen increases blood clot and uterine cancer risk and causes vaginal discharge, while Femara (letrozole) causes more joint pain and vaginal dryness.
CA
A 38-year-old member asked:

Does femara (letrozole) cause insomnia?

3 doctor answers4 doctors weighed in
Dr. Carlo Hatem
Pulmonary Critical Care 25 years experience
Yes: Femara (letrozole) causes insomnia in 7% of people who take it.
A 25-year-old member asked:

What is the difference between femara (letrozole) and arimidex?

2 doctor answers4 doctors weighed in
Dr. Cayce Jehaimi
Pediatric Endocrinology 21 years experience
Both AI: Femara (letrozole) is letrazole, an aromatase inhibitor that is slightly more potent than Arimidex though belong to the same class of drugs.
CA
A 35-year-old member asked:

Will I ovulate while on femara (letrozole)?

2 doctor answers6 doctors weighed in
Dr. Andrea Knittel
Dr. Andrea Knittelanswered
Obstetrics and Gynecology 8 years experience
Most likely: Femara is the brand name for the drug letrozole, which is an aromatase inhibitor. This kind of drug blocks production of estrogen, making the body think it should create a surge of hormones like those that prompt ovulation. Letrozole is sometimes used in women being treated for infertility to induce ovulation. In post-menopausal women, ovulation will not occur, and Letrozole has other uses.
A 30-year-old member asked:

What are differences between femara (letrozole) and arimidex ?

1 doctor answer5 doctors weighed in
Dr. Devon Webster
Medical Oncology 22 years experience
The names and doses: Femara (letrozole) and Arimidex are both aromatase inhibitors that are taken by mouth once a day. They work by prevenitg fat cells from making estrogen, which lowers total estrogen in your body. We use them identically in practice.
Dr. Andrew Turrisi
Radiation Oncology 47 years experience
And price!
Aug 17, 2012

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Last updated Mar 29, 2019

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