A 36-year-old member asked:
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does femara (letrozole) cause osteoporosis?

2 doctor answers
Dr. Quang Nguyen
Specializes in Endocrinology
Possibly: Femara (letrozole) is an aromatase inhibitor. It works by decreasing the amount of estrogen produced in post-menopasual women. Anything that lowers estrogen level will take away its protective effect on bone, thus increasing the risk of fracture, osteopenia or osteoporosis.
Answered on Mar 22, 2020
Dr. Joseph Newman
32 years experience Podiatry
It can: It is known to cause bone density loss, ie osteoporosis. Consult with your doctor regarding this.
Answered on Mar 13, 2013

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