A member asked:

Can you dissolve femara (letrozole) in water?

5 doctors weighed in across 2 answers

Ask prescribing Dr.: A person who is taking Femara (letrozole) (for breast cancer) and has trouble swallowing the pill, should ask the prescribing doctor if the pill can be crushed and mixed with liquid or food. The paperwork about the drug says the drug doesn't dissolve well in water. It doesn't have a warning box saying not to crush the tablet, so probably it is ok to crush up to aid swallowing.

Answered 2/9/2019

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Dr. Cynthia Anderson answered

Specializes in Radiation Oncology

Not recommended: It is better to take the pill intact and let it dissolve in your stomach. It is meant to dissolve and release the medicine over time. Dissolving it may flood your system too quickly or not be absorbed properly.

Answered 7/21/2017

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