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A member asked:
How come there is a warning for not eating grapefruit with flomax (tamsulosin)?
A doctor has provided 1 answer
Furanocoumarins...: Are compounds present in grapefruit that inhibit certain enzymes (cyp3a4) that are important in the metabolism of drugs. Since they are inhibited, a higher dose of the drug ends up in the circulation, increasing the therapeutic effects, adverse effects, & toxicity. Caution is advised regarding tamsulosin (flomax) use, but no deaths have been reported.
Answered 9/21/2014
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