A member asked:

Which is most effective; hydrocodone, fentanyl, oxycodone, or methadone?

5 doctors weighed in across 2 answers

All different: They have different uses and modes on administration. Hydrocodone and oxycodone are taken by mouth and last about 3-4 hours. Methadone takes several hours to days for its full effect and last a very long tie. Fentanyl is available through a patch or IV and is short acting and extremely potent.

Answered 6/8/2016

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Dr. Ron Jones answered

Specializes in Family Medicine

No such thing: It is not what is most effective, it is what is best for you. I am sure your doctor will choose the safest type of opioid to treat your pain and see how you respond. If you do not respond, then he/she may try a different opioid. The most important thing is to find out what is causing a pain bad enough to require and opioid.

Answered 5/26/2018

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