What is the best way to lose weight on certain parts of my body?

Several: Wt loss is a whole body phenomenon.Exercise, consume low glycemic index foods, increase fish/fishoil consumption, good contoll of diabetes if a pt has this condition. Otherwise you can certainly tone certain body parts with targeted exercise but wt loss is going to involve burning more calories than you consume to create a caloric defict. It should be done slowly and safely with input from ur dr.