A 39-year-old member asked:
what leads to or causes tardive dyskinesia?
2 doctor answers
Dr. Felix Brizuela answered
31 years experience Neurology
"phenothiazines": Tardive means drug induced. Caused mainly by older major tranquilizers, also called typical anti-psychotics such as Haldol but also can happen with anti-nausea drugs like Reglan (metoclopramide) or Compazine that are structurally similar to Haldol type drugs. It is due to inhibition of Dopamine in the part of the brain called the basal ganglion.
Answered on Sep 22, 2016
Dr. William Singer answered
50 years experience Pediatric Neurology
Tardive dyskinesia: Tardive dyskinesia is most often a side effect of the use of antipsychotic medications when weaned, but can occur during treatment. If recognized early it may be temporary if the medication is discontinued. The symptoms can result from an excessive amount of the brain chemical Dopamine or excessively sensitive receptors for Dopamine present on certain brain cells involved in movement.
Answered on Apr 21, 2016
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