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A 45-year-old member asked:

meaning of troponin i elevation?

1 doctor answer2 doctors weighed in
Dr. Christopher White
Cardiology 43 years experience
Heart Muscle Damage: Troponin i and t are biomarkers that are very sensitive and specific for heart muscle damage (heart attack). When these are elevated, they usually (but not always) indicated a heart attack. There are some exceptions, so you should speak with a physician to clarify this issue.

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A 30-year-old member asked:

Can you explain why troponin levels increase when there is cardiac damage?

2 doctor answers3 doctors weighed in
Dr. Shahin Tavackoli
Cardiology 23 years experience
See my other answer: Please see my other answer regarding this subject. In short, there should not be much troponin in blood in a patient without cardiac damage. Troponin is part of the structure of the heart muscle and when the muscle is damaged, it "leaks" into the blood stream. That is an oversimplification but it is pretty close to the truth of what happens.
Dr. Christian Assad
Cardiology 14 years experience
Troponins are protein molecules that are part of cardiac and skeletal muscle. Smooth muscle cells do not contain troponins. They are generally undetectable in healthy patients. The absolute abnormal value varies depending on the clinical setting and if there is kidney insufficiency trop could also be elevated since it is cleared by them.
Dec 29, 2014
A 38-year-old member asked:

What is cardiac-specific troponin t?

2 doctor answers7 doctors weighed in
Dr. Martin Bress
Internal Medicine 50 years experience
A biomarker: Measurement of troponin t is used to help make the diagnosis of myocardial infarction (heart attack). The chemical leaks from damaged heart muscle and confirms injury to the heart. A new assay called highly sensitive troponin is now available and is 10 times more sensitive and increases the speed and accuracy of the diagnosis. If the result is negative 3 hours after chest pain, mi is unlikely.
A 47-year-old member asked:

What is the difference between troponin I and troponin t?

2 doctor answers4 doctors weighed in
Dr. Mark Rasak
Cardiology 33 years experience
Same but diffrent: The troponin is part of the heart muscle that regulates contraction. There are 3 components trop i, trop t and trop c. When damage is doneto the heart you can measure the levels of t-i and t-t . Trop i is 90% sens and 95 specific. Trop t is around 85% sensitive and 80% specific. They rise over 3 to 6 hrs and peak at 24 hrs . Can stay up to 10 days. Both are used to diagnose and risk stratify ami
A 31-year-old member asked:

What is the role of troponin in the human body?

1 doctor answer1 doctor weighed in
Dr. Liviu Klein
Cardiology 23 years experience
Cardiac protein: Troponin is a cardiac protein that contributes to the cardiac muscle fibers contraction; there are several types of troponins. They can be released in the blood stream in case of a heart attack and be used as markers for that.
China
A 33-year-old female asked:

I was fasting 12 hrs when they took my platelet count and result is 494. Could it be the reason for the elevation? Should I worry?

2 doctor answers6 doctors weighed in
Dr. Alan Faustino
Internal Medicine 26 years experience
No: It should not matter if you were fasting or not. Platlets can go up and down on a daily basis without it being an issue. We worry when it gets to around 600 and stays there and even then it could be of no concern. It can be part of myloproliferative disorders call thrombocytosis, why did you get blood work done? You should get it rechecked on a couple of weeks.

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Last updated Mar 19, 2014
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