A member asked:

Are big pathes of hyperpigmentation on the skin common in lupus?

2 doctors weighed in across 2 answers
Dr. Morris Westfried answered

Specializes in Dermatology

Yes: However this is more common in a condition called morphea which is localized scleroderma.

Answered 3/26/2013

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Dr. Bryan Wu answered

Specializes in Pathology

It can happen.: In individuals with lupus and skin involvement, the pattern of inflammation seen microscopically is an interface pattern. Inflammatory cells in this pattern involve the junction of the epidermis and dermis. Melanocytes are located in this area, and the pigmentation of epidermal cells is disrupted. In some individuals, this results in hyperpigmentation; in others, there can be hypopigmentation.

Answered 3/24/2013

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