If thyroglob autoantibodies are high (139) but tsh low (.01) and free t4 and t3 (liothyronine) normal, what is likely diagnosis? symptom includes recent-onset fatigue

Need more infomation: The test results you describe suggest early autoimmune thyroid disease, possibly graves disease, but the pattern isn't clear. If symptoms progress, redoing the tests in 3-6 months may clarify, and ultrasound or nuclear scan of the thyroid can also help. This type of problem is slow to make itself known, so regular follow up with your doc is very important.

Thyroid diagnosis: While one cannot be certain from these data, the most common entity that fits this description is hashimoto's autoimmune thyroiditis. In the early phase, because of the inflammatory reaction in the thyroid gland, more thyroid hormone is released causing the TSH to go low, and sometimes the T4 to go high; after time the inflammation settles down, and the TSH starts to go up, and the T4 goes down.

TPO antibodies?: Sounds like you could have an autoimmune thyroiditis. It would be useful to know if you have anti thyroperoxidase antibodies. You have a risk for becoming hypothyroid, so you should check your tests periodically. Talk to your doc about how often. I hope they have also felt your thyroid to be sure you don't have any nodules.

Autoimmune thyroid: You may have been hyperthyroid and are now going into hypothyroid. The TSH changes much more slowly than the T3 (liothyronine) and t4. Remeasure the tests in 1-2 months if you have symptoms, longer if not.

Abnormal lab test: You have to check the WBC count and thyroid us , plus iodine . In order to determine if you have hashimoto or grave disease, or the gland is under attack for the WBC . Also determine another lab test ate related to . If the TSH is low , also check the prolactin levels plus a complete physical examination. A question : are you taking any thyroid hormone over the c. Or any tx for, can change results.