At what age do attacks of hereditary angioedema start?

Most before age 15: About 40% of people with hereditary angioedema( hae) experience their first episode before age 5, and 75% present before age 15. There is one type of hae(type 3), found in the second decade of life or later, and rarely occurs before puberty.

Most before puberty: 40% of individuals with hereditary angioedema (hae) have attacks before age 5 and 75% have attacks before age 15. Swelling is not itchy and there are no hives in hae. Frequency of attacks increases after puberty. Diagnosis usually made in 2nd or 3rd decade of life by history with confirmatory blood tests. See your md for diagnosis and if indicated preventive treatment.

HAE presentation: One should keep in mind that the angioedema of hae is not associated with hives. Additionally, the swelling does not respond to antihistamines and corticosteroids.