Whats hereditary angioedema?

Severe Swelling: Hereditary angioedema is rare but serious genetic immune system problem that is due to a deficiency of c1 esterase inhibitor. It is characterized by swelling of the face and airways, and my be life threatening.

Different types: There are several different types of hereditary angioedema. The most common forms are the result of a deficient protein, called c1 esterase inhibitor, or because this protein does not work correctly. Other forms of hae may be related to hormone problems.

Recurrent swelling: Hae is a blood disorder that leads to episodic attacks of recurrent swelling of the face, lips, tongue, throat, extremities, or other areas of the body. Swelling of the intestines can also lead to severe abdominal pain and vomiting. Triggers include trauma, surgery, dental work, menstruation, some medications, viral illness and stress. Diagnosis is made based on clinical history and via bloodwork.

Swelling hereditary: Hereditary angioedema is an inherited disorder of c1 inhibitor that is involved in inflammatory reactions. This deficiency lead to swelling of skin, larynx, and abdominal pain occurring recurrently. The deficiency runs in the family. The episodes are usually self limited.

Genetic disorder: HAE is genetic disorder resulting in unpredictable swelling of any part of the body. It is not caused by histamine, but a chemical caused bradykinin. When released in uncontrolled manner the part of the body where this occurs swells. Swelling occurs within 6-36 hours and if untreated resolves in 2-5 days. There is now a replacement enzyme for Type I and II. 4 on demand meds are FDA approved.