Hereditary angioedema - can anybody tell me anything about?

Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may to prone to swelling problems which can be life threatening.

Non allergic swells: HAE is a deficiency or dysfunction of C1 esterase inhibitor. It results in the unregulated release of "bradykinin" a potent vasodilator. 75% of pts have a family history and 25% have it based on a spontaneous mutation. Many v/effective treatments are now available directed at different points of the "cascade" leading to bradykinin release. Oral as opposed to injectable therapies are coming soon!