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A 47-year-old member asked:

can anyone have hereditary angioedema?

2 doctor answers3 doctors weighed in
Dr. Andrew Murphy
Allergy and Immunology 29 years experience
Yes: Hereditary angioedema types 1 and 2 have a very strong genetic component and typically runs in families. However, spontaneous mutations can occur and hae i and ii can occur on anyone.
Dr. Jay Kashkin
Allergy and Immunology 38 years experience
Yes: 75% of HAE pts have the disease based on genetics (autosomal dominant). 25% have a spontaneous mutation. 50% of pts will have an attack by age 10 years and and then a larger proportion of pts during puberty. Type I (85% of pts) is based on low levels and low function of C1 inhibitor. Type II involves normal or elevated C1 inhib levels but low function. Both look exactly alike clinically.

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A 25-year-old member asked:

Is hereditary angioedema different from regular angioedema?

2 doctor answers5 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
Inherited v acquired: Angioedema, a condition involving rapid swelling & accumulation of fluid in the skin & deeper tissues, is usually classified as hereditary (similar episodes run in the family) or acquired (due to medications or other allergic reaction). A third category sometimes used is idiopathic, meaning no obvious pathology or cause can be determined. Angioedema can involve the airways & cut off breathing.
A 46-year-old member asked:

What causes hereditary angioedema to occur?

1 doctor answer2 doctors weighed in
Dr. Andrew Murphy
Allergy and Immunology 29 years experience
Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may to prone to swelling problems which can be life threatening.
A 36-year-old member asked:

Anyone here treat hereditary angioedema(hae)?

3 doctor answers5 doctors weighed in
Dr. Brian Novick
Allergy and Immunology 43 years experience
A 40-year-old member asked:

Hereditary angioedema - can anybody tell me anything about?

2 doctor answers4 doctors weighed in
Dr. Andrew Murphy
Allergy and Immunology 29 years experience
Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may to prone to swelling problems which can be life threatening.
A 30-year-old member asked:

Whats hereditary angioedema?

5 doctor answers10 doctors weighed in
Dr. Stephen Friedman
Dermatology 41 years experience
Severe Swelling: Hereditary angioedema is rare but serious genetic immune system problem that is due to a deficiency of c1 esterase inhibitor. It is characterized by swelling of the face and airways, and my be life threatening.

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Last updated Dec 9, 2020

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