Can i overdose from my methadone dosage going up 20 mgs?

Methadone 20mg: Yes you can overdose with any drug. The real issue is you are going yo to 20mg from what dose ?5mg, 10mg? If its too much of a jump then yes you could overdose. The rule should titrate up slowly to avoid complications and side effects.

Yes: We understand how long most medicines stay in our bodies. However Methadone is different for each individual. Changing the dose of Methadone requires caution. The “half-life” of Methadone can very from 10 hours to 140 hours. An increase in Methadone for one person that is easily tolerated can be an overdose of another person.