Been on methadone for 4years. never lasts full 24hrs. feel withdrawals after 19-20 hours. i've gone up in dose over&over again and it does nothing. y?

Try buprenorphine.: Methadone theoretically has a half life of about 36 hours, although this may vary considerably from patient to patient. You may be a rapid metabolizer. I would recommend trying Buprenorphine (suboxone, others), which can be dispensed in a doctor's office, and the dose ; frequency customized according to your needs. Downside is cost; it is considerably more expensive. www.opiatecure.com.