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A 34-year-old member asked:

What is the limit of benadryl (diphenhydramine) allergy pills you should take as an adult?

2 doctor answers3 doctors weighed in
Dr. Alex Martinez
Specializes in Allergy
1-2 every 4-6 hrs: Benadryl (diphenhydramine) is an antihistamine used in the treatment of allergies. It doesn't work long so it has to be taken often. The recommended dose is 1 or 2 pills (each 25 mg) every 4-6 hours, so a maximum of 12 per day (300 mg/day). Taking any Benadryl can cause sleepiness, headaches, dry mouth, & difficulty urinating. Excess Benadryl can cause delirium, diarrhea, seizures, and even coma.
Dr. Jack Mutnick
Allergy and Immunology 17 years experience
Depends: Follow the directions on the bottle unless you have spoken with your physician who gave you a different instruction list. The maximum recommended daily dose (not all at once) is 300mg/day.

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Last updated May 6, 2015
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