A member asked:

What is the limit of benadryl (diphenhydramine) allergy pills you should take as an adult?

3 doctors weighed in across 2 answers
Dr. Alex Martinez answered

Specializes in Allergy

1-2 every 4-6 hrs: Benadryl (diphenhydramine) is an antihistamine used in the treatment of allergies. It doesn't work long so it has to be taken often. The recommended dose is 1 or 2 pills (each 25 mg) every 4-6 hours, so a maximum of 12 per day (300 mg/day). Taking any Benadryl can cause sleepiness, headaches, dry mouth, & difficulty urinating. Excess Benadryl can cause delirium, diarrhea, seizures, and even coma.

Answered 11/27/2014


Dr. Jack Mutnick answered

Specializes in Allergy and Immunology

Depends: Follow the directions on the bottle unless you have spoken with your physician who gave you a different instruction list. The maximum recommended daily dose (not all at once) is 300mg/day.

Answered 5/6/2015



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