Yes, but . . .: If any tongue or lip swelling, or difficulty breathing/swallowing, call 911 or local emergency services. Need to avoid allergen & carry EpiPen (epinephrine). www.drugs.com Interactions Checker says there's no interaction btwn Mucinex D (guaifenesin & pseudoephedrine) & Benadryl (diphenhydramine). However, only antihistamine like latter is useful for allergies. Former is combo of expectorant & decongestant.
Answered 10/26/2016
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