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A member asked:
How long does it take a 25mg benadryl (diphenhydramine) pill to start working on allergy?
4 doctors weighed in across 2 answers
25-45 min: It usually takes from 25 to 45 for a pill to start to make effect has to be dissolved and absorb into the blood stream to make effect.
Answered 3/25/2018
4.3k views
Should: Start working within the hour. But it is a low dose and sedating. You might try an Allegra or Claritin (loratadine) ( store brand ok) that is once a day and once in your system you won't be on a roller coaster of it working or not as long as you take it regularly.
Answered 5/6/2016
4.3k views
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