A member asked:

What is a lymphocyte cd20? is it a type of cancer marker?

6 doctors weighed in across 2 answers

It is a major: B-lymphocyte marker, carried by benign cells as well as malgnant cells with b-cell lineage (as opposed to t-cell lineage). The ab Rituximab has been generated against it and is a key component in treating b-cell lymphomas.

Answered 7/1/2014

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Yes: Most of your normal b-cells bear this marker. It's typically used in subclassifying malignant lymphomas that have already been diagnosed, in combination with a huge array of other markers, though it can be used to "light up" the distribution of b-cells in non-cancerous tissue as well. It's the target for Rituximab and some other new rx's.

Answered 7/1/2014

5.7k views

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