Caution: Afrin (oxymetazoline): One of the most powerful topical nasal decongestants is oxymetazoline, the active ingredient in afrin. It is extremely effective at relieving severe nasal congestion in thr setting of a cold or allergy attack. It should not be used for more than 3 days because of the tolerance effect known as tachyphylaxis, which is a form of dependency that leads to deleterious changes in the nasal lining.
Answered 4/4/2016
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