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A 45-year-old member asked:

Can ssris and mdma adversely affect each other?

1 doctor answer3 doctors weighed in
Dr. Byron Law-Yone
Psychiatry 56 years experience
Yes.: Ssris increase serotonin levels and can cause life threatening serotonin syndrome. Mdma (ecstacy) is a stimulant that can deplete serotonin levels, damage brain cells, cause stroke, heart attack or death.Taking either one is dangerous.Ecstacy can make you depressed and/or negate the benefits of the ssri don't even think of taking them together.
Last updated Dec 9, 2013
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