A member asked:

How long does methotrexate stay in your body for?

4 doctors weighed in across 2 answers
Dr. Ralph Morgan Lewis answered

Specializes in Family Medicine

Depends on…: Dose & how long you were on it. Mtx's half life (amount of time for active med to be reduced by 1/2) is given as 3-15 hours but varies according the dose. It takes at least 4-5 half lives for a drug to be eliminated from the system, assuming there is normal liver & kidney function.

Answered 12/9/2013

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Dr. Thomas Namey answered

Specializes in Rheumatology

It lasts: @ and one half months for it and its polyglutamates to leave your body. We tell women desiring pregnancy to wait for three months.

Answered 2/3/2018

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