Methotrexate: Methotrexate has an elimination half life of 3 to 10 hours, therefore it will take approximately 55 hours,about 2.3 days for it to be totally out of your system.
Answered 9/26/2016
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A bit variable: Depending on high dose or low dose, interestingly the half life of this drug is a bit variable. But in general it takes about 5 half life's for a drug to be eliminated from your system. So on the long side, it would be around 75 hours or a little over three days.
Answered 8/28/2014
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