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A 42-year-old member asked:

The doctor prescribed melpalan, velcade (bortezomib) and dexamethasone for 78 yrs old male with multiple myeloma. he later increase the dose of melphalan from 10 mg to 14 mg despite the treatment progress. is this warranted considering high ast and alt?

1 doctor answer3 doctors weighed in
Dr. Herbert Duvivier
Hematology and Oncology 35 years experience
Speak with physician: The best advice at this point is to speak with the treating physician and ask for an explanation regarding the increase in the medication given the progression of disease on the current treatment. If you are not satisfied with the explanation then by all means seek a second opinion consultation. At times, changes in regimens are easily explained; don't be afraid to ask.
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Last updated Mar 1, 2019

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