A member asked:

Can you tell me what became of the investigational drug amn-107 for gist tumors?

2 doctors weighed in across 2 answers

Complicated: A phase 1 trial has been completed and reported, but a phase 2 trial comparing amn107, or nilotinib, to imatinib (gleevec), was closed early due to interim analysis showing nonsuperiority. It is being tried in combo with Gleevec in other trials. Fox chase has a trial. Nccn guidelines accept nilotinib as a treatment option but it's use is still off-label for now in gist.

Answered 10/3/2016

5.7k views

Thank

Amn-107 is TASIGNA (nilotinib): Amn 107 tasigna (nilotinib) is used for CML ( chronic myeloidleukemia ) especially if resistant to Gleevec fda did not aprove for gastointestinal stromal cell tumors ( gist ).

Answered 6/25/2014

5.7k views

Thank

Related Questions

A member asked:

Fatty tissue or cancerous tumor, how to tell?

A doctor has provided 1 answer

A member asked:

What can you tell me about the tumor necrosis factor?

A doctor has provided 1 answer

A member asked:

Can you tell me about connection to cancer and tumors.?

A doctor has provided 1 answer

A member asked:

Could you tell me if tumor and resection went fine why chemo?

A doctor has provided 1 answer