Get Virtual Care
For Businesses
About Us
A member asked:
Can you tell me how kit inhibitor help us to fight against gist?
A doctor has provided 1 answer
Pathway block: The mechanism by which imatinib (Gleevec) works is to stop cell-proliferation actions of the KIT and PDGFRA tyrosine kinases which are growth factor receptors. They initiate a signaling pathway which causes the cell to proliferate. Signaling normally occurs only when KIT or PDGFRA receptors are triggered by ligands.. These are blocked by Gleevac
Answered 8/5/2014
3.8k views
Thank
Related Questions
A member asked:
Dear doctors, as a person with ankylosing spondylitis, could you tell about the price of tnf-inhibitors, such as etanercept, infliximab, adalimumab?
A doctor has provided 1 answer
A member asked:
At my last check up, I forgot to tell the doctor about my ACE inhibitor use. Is that important?
7 doctors weighed in across 2 answers
A member asked:
I want to use(skin eraser kit- by zenmend) can you tell me its good or not.
A doctor has provided 1 answer
People also searched for:
How does imatinib stop the signaling pathway of mutated kit in patients with gist?
Can you tell me what became of the investigational drug amn-107 for gist tumors?
I am 54 woman with celiac disease and I'm about 20 pounds underweight. I also have a small polyp in the lining of my stomach called a stromal gist. What is that? I will have a 2nd scope with ultrasound in June. I am worried. Can you tell me what your op
Can you tell me about loop diuretics, analgesices, atb, arbs, ccbs, ACE inhibitors etc?
Can you tell me what the ACE inhibitor is?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HIPAASecure
SOC 2 Type 2Certified
JCAHOAccredited
Download HealthTap
Video visit and message your doctor
