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A member asked:
I've seen metformin as having weigh loss and weight gain listed as side effect. might certain health conditions predispose me for one or the other?
A doctor has provided 1 answer
Maybe.: Metformin usually induces modest wt loss of a few lbs. I have never seen anyone gain weight. The mechanism for wt loss is debated- might be related to decreased circulating Insulin levels but may also be due to direct GI irritation / stimulation ( nausea or diarrhea). Any underlying GI disease or "sensitive" gut might predispose you to weight loss.
Answered 6/25/2014
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