A member asked:

What is the difference between prozac (fluoxetine) and sertraline? the doc just switched my partner from 40mg of prozac, (fluoxetine) to 50mg for 15days, then she ups it to 100

6 doctors weighed in across 2 answers

Similar: Both of these medications are selectiveserotonin reuptake inhibitors. Each has different qualities but they are in the same class. Differences with newer antidepressants are subtler and also mostly confined to side effects. Evidence suggests that sertraline may work better than fluoxetine (prozac) for some subtypes of depression. Sertraline is effective for the treatment of panic disorders as well.

Answered 5/7/2016

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Dr. William Holmes answered

Specializes in Child Psychiatry

Similar Medicines: Prozac (fluoxetine) and zoloft (sertraline) beling to the same group of antidepressants. They are helpful about the same percentage of the time, but some individuals will do much better with one versus the other. The eventual dose of 100mg of sertraline is an average adult dose. The maximum recommended dose is 200mg per day, so there is room to work with the dose if needed and if tolerated.

Answered 12/30/2016

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