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A member asked:
What does small m protein and igg lambda spike mean?
A doctor has provided 1 answer
Monoclonal M-spikes : Antibodies such as igg are usually polyclonal. This means that many different b-cells are making antibodty with many different binding specificities. Monoclonal (m-spikes) suggest that the origin of the antibody is from one clone of blood cells, all originating from a sinle progenitor. This could mean a pre-malignant or malignant populations of cell are present.
Answered 2/18/2020
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