Sleepiness: The major side-effect of zyrtec (cetirizine) is sedation - sleepiness, fatigue, and slowed reaction time. This occurs in 1 out of 10 or 1 out of 12 users. Compare to Benadryl (diphenhydramine) 1 of 3 users or clariting 1 in 50 users. Also occasionally reported are stomachache, headache, diarrhea, constipation & dry mouth & throat. In older men zyrtec can sometimes cause difficulty with urination.
Answered 6/24/2014
5.8k views
Minimal side effects: The side effects of zyrtec (cetirizine) are minimal compared to old antihistamines. Very small incidences of headache, sleepiness, abdominal pain, dry mouth, and nose bleeds have been reported.
Answered 1/2/2019
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3 doctors weighed in across 2 answers
A doctor has provided 1 answer
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