Collagenase: Marketed as xiaflex, (collagenase clostridium histolyticum) this is a form of Collagenase that gets injected into dupuytrens cords in the palm of the hand. At a second stage the following day, once the cord is weakened by the collagenase, the cord can be disrupted. This is a fairly straightforward office procedure and has certain advantages over surgery in many situations. See more at www.Myhandhealth.Com, click on duputytrens/xiaflex.
Answered 6/24/2014
5.8k views
None: Dupuytren's disease is not helped by medication. Unfortunately we do not know of anything that will stop or prevent the disease. There is a new treatment for dupuytren's where an enzyme, collagenase, is injected into the abnormal tissue to dissolve and weaken it. A hand surgeon can give you more information about it, or visit www.Xiaflex.Com.
Answered 6/30/2012
5.8k views
Only one: Dupuytren's contracture is a genetically mediated fibroproliferative disorder, which causes contractures of the fingers. The only fda approved medical treatment for dupuytren's contracture with a palpable cord is xiaflex (collagenase clostridium histolyticum). Xiaflex (collagenase clostridium histolyticum) is a collagenase, which is an enzyme that breaks down collagen. Collagen build-up leads to contracture. Once dissolved, the finger can be straightened in the office.
Answered 9/28/2016
5.7k views
Dupuytrens info: Some alternatives include needle aponeurotomy, limited fasciaotomy and xiaflex (collagenase clostridium histolyticum) or collagenase <a also http://www.Handsurgerypodcast.Com/dupuytrens-disease.Html.
Answered 4/7/2020
5.4k views
No oral medications: No oral medications affect dupuytrens, but there is an injectable "medication" that acts to dissolve a portion of the dupuytrens cord. Best to discuss this medication with a hand specialist.J.
Answered 6/15/2014
5.4k views
Xiaflex (collagenase clostridium histolyticum): Xiaflex (collagenase clostridium histolyticum) is the only fda drug approved and found to be successful in treating dupuytren's contracture.
Answered 3/12/2013
5.3k views
Xiaflex (collagenase clostridium histolyticum): Xiaflex (collagenase clostridium histolyticum) is a medication that is injected into the dupuytrens cord in the hand to dissolve the collagen and release the contracture. It is been out for a few years and has had promising results as an alternative to open surgical treatments.
Answered 11/25/2013
5.3k views
Xiaflex (collagenase clostridium histolyticum): Xiaflex (collagenase clostridium histolyticum) is a medication injected into the cord which ruptures it, releasing the contracture but it does recur. There is no cure
Answered 2/28/2015
3.2k views
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