A member asked:

What medications treat dupuytren's disease?

11 doctors weighed in across 8 answers

Collagenase: Marketed as xiaflex, (collagenase clostridium histolyticum) this is a form of Collagenase that gets injected into dupuytrens cords in the palm of the hand. At a second stage the following day, once the cord is weakened by the collagenase, the cord can be disrupted. This is a fairly straightforward office procedure and has certain advantages over surgery in many situations. See more at www.Myhandhealth.Com, click on duputytrens/xiaflex.

Answered 6/24/2014

5.8k views

Thank
Dr. F. Thomas Kaplan answered

Specializes in Hand Surgery

None: Dupuytren's disease is not helped by medication. Unfortunately we do not know of anything that will stop or prevent the disease. There is a new treatment for dupuytren's where an enzyme, collagenase, is injected into the abnormal tissue to dissolve and weaken it. A hand surgeon can give you more information about it, or visit www.Xiaflex.Com.

Answered 6/30/2012

5.8k views

Thank

Only one: Dupuytren's contracture is a genetically mediated fibroproliferative disorder, which causes contractures of the fingers. The only fda approved medical treatment for dupuytren's contracture with a palpable cord is xiaflex (collagenase clostridium histolyticum). Xiaflex (collagenase clostridium histolyticum) is a collagenase, which is an enzyme that breaks down collagen. Collagen build-up leads to contracture. Once dissolved, the finger can be straightened in the office.

Answered 9/28/2016

5.7k views

Thank
Dr. Jeffrey Wint answered

Specializes in Hand Surgery

Dupuytrens info: Some alternatives include needle aponeurotomy, limited fasciaotomy and xiaflex (collagenase clostridium histolyticum) or collagenase <a also http://www.Handsurgerypodcast.Com/dupuytrens-disease.Html.

Answered 4/7/2020

5.4k views

Thank
Dr. Matthew Welsch answered

Specializes in Hand Surgery

No oral medications: No oral medications affect dupuytrens, but there is an injectable "medication" that acts to dissolve a portion of the dupuytrens cord. Best to discuss this medication with a hand specialist.J.

Answered 6/15/2014

5.4k views

Thank
Dr. Gary Pess answered

Specializes in Hand Surgery

Xiaflex (collagenase clostridium histolyticum): Xiaflex (collagenase clostridium histolyticum) is the only fda drug approved and found to be successful in treating dupuytren's contracture.

Answered 3/12/2013

5.3k views

Thank
Dr. Mark Ciaglia answered

Specializes in Hand Surgery

Xiaflex (collagenase clostridium histolyticum): Xiaflex (collagenase clostridium histolyticum) is a medication that is injected into the dupuytrens cord in the hand to dissolve the collagen and release the contracture. It is been out for a few years and has had promising results as an alternative to open surgical treatments.

Answered 11/25/2013

5.3k views

Thank
Dr. Teddy Atik answered

Specializes in Hand Surgery

Xiaflex (collagenase clostridium histolyticum): Xiaflex (collagenase clostridium histolyticum) is a medication injected into the cord which ruptures it, releasing the contracture but it does recur. There is no cure

Answered 2/28/2015

3.2k views

Thank

Related Questions

A member asked:

What is dupuytren's disease caused by and what can be done about it?

9 doctors weighed in across 3 answers

A member asked:

When should someone have surgery for dupuytren's disease?

2 doctors weighed in across 2 answers

A member asked:

Dupuytren's disease, can you tell me about the operation?

4 doctors weighed in across 2 answers

A member asked:

Can peyronies disease cause dupuytrens contractures?

2 doctors weighed in across 2 answers