How would a man be diagnosed with prostate cancer?

By you MD: First examination by your md , if repeat psa levels are still elevated , biopsy of prostate is still gold standard. If biopsy is negative and still suspicious for malignancy, testing for the genetic marker pca3 is helpful to detect the presence of carcinoma..

Biopsy: The only way to confirm a diagnosis of prostate cancer is to perform a biopsy. Other tests may be suggestive of cancer but only a biopsy can prove it.